in the UK everyone over 65 will receive another covid booster injection this autumn/winter,
photograph Wikipedia, the article is here, so the next question, which arm to have the jab? before you say the usual one, normally not the dominate arm, have a read of this part of a text in the journal eBioMedicine, (part of The
Lancet),
'both
ipsilateral and contralateral vaccination induce a strong immune response, but
secondary boosting is more pronounced when choosing vaccine
administration-routes that allows for drainage by the same lymph nodes used for
priming. Higher neutralizing antibody activity and higher levels of
spike-specific CD8 T-cells may have implications for protection from infection
and severe disease and support general preference for ipsilateral
vaccination... The observed differences in immunogenicity may result from the
fact that priming and secondary boosting of the immune response after
ipsilateral vaccination occurs in the same draining axillary lymph nodes with
limited involvement of the contralateral side. Conceptually, this is supported
by 18F-FDG PET/CT studies among BNT162b2-vaccine recipients demonstrating that
the ipsilateral lymph nodes on the side where the vaccine had been applied were
significantly larger in size and showed higher metabolic activity compared to
the contralateral lymph nodes',
so the usual arm or the other one? if I read the article correctly it should not be the arm used that had your first jab, or did I read it incorrectly?
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