And you thought fish were fun!



Puffer fish meat, which is known as fugu in Japan, is considered a delicacy and in Japan can only be prepared by highly trained fugu chefs. The meat contains a toxin called tetrodotoxin, or TTX, which is produced by bacteria living within the fish and can prove deadly if small quantities are consumed.Trained fugu chefs leave trace quantities of the poison in the fish meat, which causes a tingling sensation on the tongue when the fish is eaten. However, too much of the toxin can result in paralysis, asphyxiation and heart failure.

Tetraodotoxin, there are thought to be around 120 species of puffer fish. Parts of the fish contain a toxin called tetradotoxin which can be up to 1200 times more poisonous than cyanide. There is enough poison in a single puffer fish to kill 30 people. However, the fish known as fugu in Japan is also considered a delicacy in parts of the world and in Japan chefs have to have a special license to prepare it.Symptoms of tetradotoxin poisoning can occur anything from 15 minutes to several hours later and include numbness, nausea, vomiting, extreme stomach pains and sometimes paralysis and death.

only eat fugu,
in genuine fugu resturaunts!
There is no known antidote to tetradotoxin poisoning. It’s not all doom and gloom however, this month WEX Pharmaceuticals Inc in Canada have just entered Phase 3 trials of Tectin™ - the active ingredient of which is tetrodotoxin - to treat extreme pain in cancer sufferers and withdrawal symptoms in heroin addicts. Previous trials have shown a 71% success rate in effectively treating pain and suggest that the drug may be as much as 3,000 times as effective as morphine.
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